Delfini Publication: Creating evidence-based drug monographs and drug class reviews
Formulary®: a peer-reviewed drug management journal for managed care and hospital decision-makers
Process steps and suggestions for creating drug monographs and drug class reviews in an evidence-based formulary system
Strite SA, Stuart ME, Urban S. Process steps and suggestions for creating drug monographs and drug class reviews in an evidence-based formulary system. Formulary. April 2008;43:135–145.
Abstract
Given the high estimates of inappropriate healthcare decisions in this
country and the well-documented evidence of inappropriate variations in
healthcare, a well-functioning formulary system is of great importance.
Bias in research tends to inflate or falsely report benefit in clinical
trials of interventions by up to a relative 40% to 50%. Therefore, to
ensure the adoption of products with valid and clinically useful outcomes,
formulary systems should include in their processes the key steps used
in evidence-based medicine, including the evaluation of therapeutic studies
for bias and clinical usefulness to inform formulary decisions. This article
outlines requirements and suggestions for obtaining studies with appropriate
designs and acceptable methodology and execution, and emphasizes why such
studies should be the basis for developing drug monographs and class reviews
and informing decisions. (Formulary. 2008;43:135–145.)
Online and downloadable version [PDF]
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